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Harmfull Effects of Smoking

Cigarette smoking is the leading cause of preventable death in the United States.1

  • Cigarette smoking causes more than 480,000 deaths each year in the United States. This is nearly one in five deaths.1,2,3

  • Smoking causes more deaths each year than the following causes combined:4

    • Human immunodeficiency virus (HIV)

    • Illegal drug use

    • Alcohol use

    • Motor vehicle injuries

    • Firearm-related incidents

Cigarette smoking increases risk for death from all causes in men and women

Smokers are more likely than nonsmokers to develop heart disease, stroke, and lung cancer.1

  • Estimates show smoking increases the risk:

    • For coronary heart disease by 2 to 4 times1,6

    • For stroke by 2 to 4 times1

    • Of men developing lung cancer by 25 times1

    • Of women developing lung cancer by 25.7 times1


  • Smoking causes diminished overall health, increased absenteeism from work, and increased health care utilization and cost.

Smokers are at greater risk for diseases that affect the heart and blood vessels (cardiovascular disease).1,2

  • Smoking causes stroke and coronary heart disease, which are among the leading causes of death in the United States.1,3

  • Even people who smoke fewer than five cigarettes a day can have early signs of cardiovascular disease.1

  • Smoking damages blood vessels and can make them thicken and grow narrower. This makes your heart beat faster and your blood pressure go up. Clots can also form.

  • A stroke occurs when:

    • A clot blocks the blood flow to part of your brain;

    • A blood vessel in or around your brain bursts.1,2


  • Blockages caused by smoking can also reduce blood flow to your legs and skin.

Smoking can cause lung disease by damaging your airways and the small air sacs (alveoli) found in your lungs.1,2

  • Lung diseases caused by smoking include COPD, which includes emphysema and chronic bronchitis.1,2

  • Cigarette smoking causes most cases of lung cancer.1,2

  • If you have asthma, tobacco smoke can trigger an attack or make an attack worse.1,2

  • Smokers are 12 to 13 times more likely to die from COPD than nonsmokers.

Smoking can cause cancer almost anywhere in your body:1,2

  • Bladder

  • Blood (acute myeloid leukemia)

  • Cervix

  • Colon and rectum (colorectal)

  • Esophagus

  • Kidney and ureter

  • Larynx

  • Liver

  • Oropharynx (includes parts of the throat, tongue, soft palate, and the tonsils)

  • Pancreas

  • Stomach

  • Trachea, bronchus, and lung

Smoking harms nearly every organ of the body and affects a person’s overall health.1,2

  • Smoking can make it harder for a woman to become pregnant. It can also affect her baby’s health before and after birth. Smoking increases risks for:1,2,5

    • Preterm (early) delivery

    • Stillbirth (death of the baby before birth)

    • Low birth weight

    • Sudden infant death syndrome (known as SIDS or crib death)

    • Ectopic pregnancy

    • Orofacial clefts in infants.


  • Smoking can also affect men’s sperm, which can reduce fertility and also increase risks for birth defects and miscarriage.2

  • Smoking can affect bone health.1,5

    • Women past childbearing years who smoke have weaker bones than women who never smoked. They are also at greater risk for broken bones


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